Skin Care and Glutathione

The Ultimate Anti-Aging Skin Treatment

Why is skin care so important in anti aging therapy?

Our skin is considered the largest organ of the human body. It is our first line of defense and therefor it is the most easily damaged. Before looking at the anti aging aspect of skin care, lets look at the basics.

The two major divisions of the skin are the dermis and epidermis. The dermis has four or five layers depending on the type of skin. It is just above the inner most layer of the epidermis that the primary phagocytosis (fighting off insurgent attackers like germs, viruses, and chemical exposures) takes place.

These cells once formed rise to the surface to be shed. This process has been estimate to take from 45 to 75 days.

Commonalities

Some common problems related to skin care...

Abnormal Dryness: abnormal deficiency of thyroid function, diabetes and other conditions.

Ashen: Malignant diseases, sever anemia, cancers, tuberculosis, chronic interstitial nephritis.

Bronzing: Addison's disease, poisoning with certain dyes, poisoning with certain metals, early stages of pellagra.

Brownish-yellow spots could be related to several diagnosis including liver and uterine malignancies.

Cherry red: carbon monoxide poisoning.

Yellow cast or Golden Hue:Jaundice or even Gallbladder blockage.

These are just a few of the many conditions as indicated by skin color that require skin care.

In addition to maintaining temperature, sensation, synthesis of vitamin D, it protects the body from pathogens, chemical, photo, and air born insurgents trying to wreak havoc on our body.

In contrast, some medications can be delivered to the body through the skin. Nicotine transdermal patches and some pain medications work this way. To be effective, the pain medications need to be on people with sufficient fat stores or little pain med will be transferred and little pain relief realized.

Hygiene

There is a constant releasing of dead skin that is replaced with new skin. To prevent the dead skin from having a foul odor, bathing usually helps.

Sunlight, water and air all play a key role in our personal skin care.

Bugs Win-You Win

Our skin has microorganisms including yeasts and bacteria. These cannot be removed by any amount of cleaning nor would you want to. They are a part of a symbiotic skin care that keeps you healthy.

They also monitor each other and are part of a healthy skin. When there is a disturbance in the balance, overgrowth and infection may result.

One example is antibiotics that kill microbes and resulting in an overgrowth of yeast.

A similar overgrowth could happen when there is a lack of air, sun and water and or the immune system is compromised.

The worse case scenario is a bacterial infection superimposed over a fungal infection.

Aging Skin Care

The older our skin becomes the thinner it gets. This makes it more easily damaged both by injury and exposure.

A good goal would be to protect the skin or enhance the ability for the skin to protect its self.

What is the glutathione skin relationship. Like everything glutathione, it all starts with cysteine.

Notice what one study found....

1: Clin Cancer Res. 2007 Oct 1;13(19):5952-8. N-Acetylcysteine Protects Melanocytes against Oxidative Stress/Damage and Delays Onset of Ultraviolet-Induced Melanoma in Mice. Cotter MA, Thomas J, Cassidy P, Robinette K, Jenkins N, Florell SR, Leachman S, Samlowski WE, Grossman D.

Authors' Affiliations: Departments of Dermatology, Oncological Sciences, Medicinal Chemistry, Medicine, and Melanoma Program, Huntsman Cancer Institute, University of Utah Health Science Center, Salt Lake City, Utah.

Working on the premise that UV radiation is the major environmental risk factor for melanoma cancer not to mention that it is an inducer of oxidative stress, they considered the pathogenesis of several malignancies. They evaluated whether N-acetylcysteine (NAC) (Please note: This is a chemical version of what you can get naturally to boost your glutathione in your skin) could protect melanocytes from UV-induced oxidative stress or damage in vitro and from UV-induced melanoma.

This means the NAC was part of the diet of the baby mice. They are pink and their skin is close to our skin. Here is the interesting part.

Their conclusion: Their data highlighted the potential importance of oxidative stress in the pathogenesis of melanoma. This suggest that NAC may be useful as a chemopreventive agent. There are some very good reason for not taking the drug or chemical form of cysteine. More importantly, there is a natural form, one found in both a mothers milk and in nature. One that was in our diet years ago but no longer is, that is unless you supplement your diet.

If this is true, this means you could reduce your risk of cancer by simply the foods you eat.

1: Surg Today. 2006;36(4):376-81. Whey feeding suppresses the measurement of oxidative stress in experimental burn injury. Oner OZ, Oğünç AV, Cingi A, Uyar SB, Yalçin AS, Aktan AO.

Department of General Surgery, Marmara University, Tophanelioğlu cad., Altunizede, Istanbul, Turkey.

PURPOSE: Burns trigger numerous processes which may lead to multiple distant organ dysfunction. Discover by investigating the protective effect of dietary whey supplementation on organs in a rat model.

RESULTS: Glutathione (GSH) levels remained the same in the liver but were slightly elevated in the kidneys after burn injury in the rats fed a standard diet.

Supplementation resulted in a significant increase in hepatic GSH levels 4 h after burn injury. Moreover, there was a significant rebound effect in the liver and kidney GSH levels after 72 h and supplementation potentiated this effect.

Also supplementation resulted in decreased sub-epidermal inflammation.

The conclusion is that it benefits the liver and kidneys by increasing the protection of them and protects the skin from additional inflammation. However it lacked in the ability to increase healing. Thus the next study...what happens if you apply it topically.

In this study they only measured the glutathione in the skin. Other studies demonstrate success with cysteine in a tincture and applied topically such as with vitamin e oil to improve the transport of the cysteine. With any open wound it is necessary to see a doctor and be treated with sterile procedure to avoid risk of a major infection not to mention other complications.

There is much more on skin care that this space does not allow coverage. In time, we will make it available.

1: Burns. 2005 Dec;31(8):972-6. Epub 2005 Nov 8. Saving the zone of stasis: is glutathione effective?

Corlu Military Hospital, Department of Plastic and Reconstructive Surgery, 59850 Corlu, Tekirdag, Turkey. fatihzor@yahoo.com

One of the main subjects that burn researches are focused on is saving the zone of stasis. There are many molecules that are used for this purpose, but all have their drawbacks. Glutathione is one of the major buffer molecules of the cells and is known to increase the thermo-resistance of the cells.

In this study, the effect of the systemic glutathione on the zone of stasis was evaluated. The results showed that glutathione is an effective molecule for saving the zone of stasis. It is well-known cheap, and easy to use.

There is a lotion for skin care that will boost your natural glutathione. The lotion that has natural cisteine in it. This is the kind that boosts your bodies glutathione in clinical tests. See what it will do for you.

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