NAC Contraindications: Do Not Take NAC if...

NAC Contraindications or the reasons you should not take NAC if...? Here are NAC cautions or NAC restrictions. Note, we are not considering the IV complications. We are only looking at the potential problems from oral form of NAC.

N-acetylcysteine, also known as NAC, acetylcysteine, and mercapturic acid is considered a non-essential amino acid (although we believe it to be essential for treating numerous health issues) used in treating asthma, bronchitis, mercury poisoning, aging spots and has been studied in treating and resulting in beneficial results in over 60 other diseases or conditions. With all of the benefits, there are some important NAC contraindications.

You Should Not Take NAC If...

There are actually several contraindications or reasons you should not take if.....

If you choose to take any supplement on your own...and especially NAC, there are a few things you need to be aware of.

Do Not Use NAC if...

  • you have an organ transplant unless you get doctor approval
  • you have a stomach ulcer
  • Before Using NAC, Consult Your Doctor if you are...

  • using any medicine or if you are allergic to any medicine including supplements.
  • pregnant or plan to become pregnant while using this medicine
  • breast feeding
  • suffering with asthma
  • suffering with liver disease
  • suffering with asthma
  • managing high blood pressure
  • managing heart or blood vessel disease
  • Drug Interactions / NAC Contraindications

    Always speak to your doctor or pharmacist before taking any N-acetylcysteine products and especially if you are or will be taking any drugs but especially any of the following....

  • Activated charcoal
  • Ampicillin
  • Carbamazepine (Tegretol®)
  • Cephaloridine (Loridine(®)
  • Cloxacillin (Cloxapen®)
  • Methicillin (Staphcillin®)
  • Nitroglycerin (Nitrostat ®, Nitro-Dur ®, Nitro-Bid ®)
  • Isosorbide mononitrate (Imdur, Monoket, ISMO) used for the prevention of chest pain (angina)

    If you take NAC with nitroglycerin or Imdur, there is an increased risk of side effects including headache, dizziness, and lightheadedness and low blood pressure.

  • Oxacillin
  • Penicillin G
  • Quinacillin
  • Any Chemo Therapy
  • Radiation Treatments
  • Gentamicin
  • Warnings

    Large doses of N-acetylcysteine can be dangerous to nerve cells. While it helps nerve cells regrow, in large doses, it can do the opposite.

    Many websites erroneously indicate that NAC is safe even in large doses. In one test of healthy men, when given a large dose of NAC, severe health problems arose.

    The nerve damage when used in large doses is in addition to the negative results in the high dose trial.

    It should not be used if you have a stomach ulcer.

    It may cause kidney stones. It should be supplemented with vitamin C to help prevent stones.

    It should not be used if you have an organ transplant.

    Potential Side Effects:

    Immediately stop use and inform your doctor if you have...An allergic reaction such as itching or hives, swelling in the face or hands. If you have swelling in your mouth, throat, chest tightness or trouble breathing, it should also be discontinued and if necessary, emergency medical care.

    Other Side Effects:

    Rarely NAC may cause other side effects. Inform your doctor if you have side effects that you think are caused by NAC. These would include but are not limited to....

  • Fever or chills
  • Nausea (upset stomach)
  • Vomiting (throwing up)
  • Diarrhea
  • Cough, nose congestion, runny nose
  • May make asthma symptoms worse

    For those with Asthma, it may make it worse. While we have not seen this, literature suggests it may be a problem for some.

  • Storage

    It is important to keep NAC away from children.

    Keep all medicine locked up and away from children. This is especially true of NAC.

    It is not approved for children.

    Store NAC away from heat and direct light. Do not store NAC in the bathroom, near the kitchen sink, or in other places that could be exposed to dampness.

    Heat and or moisture may cause the NAC to break down and not work effectively. As with all medicine, dispose of any products that are out of date or that are not needed.

    In view of the NAC contraindications, never share your NAC with others to help them. They may have one of the above conditions or medications and not have told you.

    Note that it has a very noxious odor that comes from the bottle when you open. This is normal.

    Boost Glutathione Guide

    NAC Side Effects

    NAC and What it Does

    Go to Home

    Foot Notes

    Info on Treating Stable Renal Transplant Patients with NAC (Beneficial)

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