Immune System

To understand how to boost the immune system it would be good to know what the system is. Anyone that says you can boost your immunity is oversimplifying the process. Lets take a basic look at the immune system.

What is Immunity?

Immunity: the ability of a life form to resist or defend its self against a particular infection, disease, toxin or unwanted biological invasion (all enemy insurgents). Immunity divided into types and sub-divided into different systems.

There are three lines of defense.

  • Physical and Chemical barriers to Infection
  • Inflammatory Response
  • Immune Response
  • Tale of Two Immune Systems

    Innate and Adaptive Immune System

    Physical barriers prevent most organism from invading the body. The physical barriers are the skin and mucous membranes. They make up the major part of the innate immunity that our bodies provide. Should the insurgent get by they call upon the adaptive immunity.

    Any invader or enemy insurgent that gets past them trigger both an inflammatory and immune response. The inflammatory response is in the skin. The immune response is in the bones where the blood is made. This is part of the adaptive immunity.

    Adaptive immunity is subdivided into two major types depending on how the immune response was summoned.

    Two Types of Immunity

    Natural or naturally acquired immunity is what we inherit. It primarily works through the innate immune system.

    Our skin when it is intact, mucous membranes, even the cilia of the respiratory track along with coughing and sneezing work as part of our innate immune system and provide natural immunity.

    The Navy and Coast Guard

    The navy consists of white blood cells that work with both the natural and acquired immune responses. As with any navy, there are different types of ships that offer various protections. The three types of ships in this navy go by the acronym BEN.

    BEN stands for basophils, eosinophils and neutrophils, the three granular leukocytes.

    These help fight toxins by firing various types of defenses. Just like a battle ship that fires various ordinance, these ships sailing the seven seas of our blood stream fire off histamine, bradykinin, and prostaglandins.

    Also in the navy are Nongranular leukocytes and lymphocytes. The especially work like mine sweepers, engulfing insurgent ordinance (toxins) that got past the first line of defense such as the skin.

    There is more. This is just the basics.

    Acquired Immunity

    Acquired immunity is what you acquire during your life time.

    Immune Responses

  • phagocytic immune response
  • humoral or antibody immune response
  • cellular immune response
  • Cellular immune response involves the T cells. The T cells are there To Kill, To Help or To Suppress. T Cells are involved in the destruction of target cells. A target cell is one that has been overtaken by (infected with) an enemy insurgent, be it virus, bacteria or cancer.

    The B cells are from the bone. B cells make antibody bombs that destroy bacteria and viruses.

    So while the B cells make the antibody bombs that incapacitate the insurgent antigen, the T cells attack the antigen.

    Allergy Basics

    Don't forget the Compliment

    Humoral immunity includes the compliment cascade. Simply put, this causes the inflammatory response. Inflammation is responsible for, associated with, or some how involved with many disease processes or conditions.

    Autoimmun Rev. 2009 Jul;8(8) said in part...

    Glutathione has been demonstrated to have diverse effects on the immune system, either stimulating or inhibiting the immunological response in order to control inflammation.

    So where does the glutathione fit into all of this. A part of the navy is the Marine Corps. Called by many names through the years, one that best fits the Marine like glutathione is bullet catcher.

    Glutathione takes the bullet to save the cell. Whether it is on one of the Navy like vessels of BEN, whether it is a B or T cell.

    What happens when the enemy insurgent attacks a B cell?

    Leuk Lymphoma. 2009 May;50(5) said in part...

    Glutathione preoxidase and catalase (enzymatic antioxidants) and vitamin C and E (non-enzymatic antioxidants) were significantly declined in patients whereas malondialdehyde (MDA) levels were elevated as compared with controls.

    These results suggest that Multiple myeloma (MM) is closely associated with oxidative stress and reduced antioxidant capacity and further investigation might provide an insight to understand a putative causal link between oxidative stress and MM disease progression.

    This is a simple math equation. You have only so many marines. Once they take the bullet, they are gone. Unless reinforcements are sent in, they will eventually lose the battle. This is a condition that is being recognized as Low CG Syndrome

    Four Key Immunity Structures

  • lymph nodes
  • thymus
  • spleen
  • tonsils
  • It is within these structures that the body manages the immunity system.

    Next we will look at the how to boost immune system question. Glutathione (GSH) plays a big role in this.

    More On the Immune System

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